Pioneers in Precision Medicine

PellePharm leads the way in applying precision medicine to dermatology.

PellePharm is a biotechnology company committed to targeting rare dermatologic diseases at the source. Founded by world leaders in hedgehog signaling, PellePharm is working to improve the quality of life for those suffering from Gorlin Syndrome and BCCs by providing an easy-to-use topical solution that eliminates the need for regular, painful surgeries.

"Patients deserve something better
than just surgery alone"

Jean Tang, MD, PHD

Leadership

Sanuj Ravindran, M.D.

President, CEO & Director

ERVIN EPSTEIN, M.D.

Co-Founder, Director & Chief Medical Officer, PellePharm

GERD KOCHENDOERFER, Ph.D.

Vice President, Technical Operations & Program Management, PellePharm

ALIX ALDERMAN

Vice President of Regulatory Affairs, PellePharm

Board of Directors

Sanuj Ravindran, M.D.

President, CEO & Director

JEAN TANG, M.D., Ph.D.

Co-Founder, Medical Advisor & Director

Ervin Epstein, M.D.

Co-Founder, Director & Chief Medical Officer, PellePharm

Frank McCormick, Ph.D.

Co-Founder of BridgeBio

NEIL KUMAR, Ph.D.

Co-Founder of BridgeBio

Founders

JEAN TANG, M.D., Ph.D.

Co-Founder, Medical Advisor & Director

Ervin Epstein, M.D.

Co-Founder, Director & Chief Medical Officer, PellePharm

Philip Beachy, Ph.D.

Co-Founder

Investors

BridgeBio is a clinical-stage biotech company developing novel, genetically targeted therapies to improve the lives of patients. The BridgeBio approach combines a traditional focus on drug development with a unique corporate model, allowing rapid translation of early stage science into medicines that treat disease at its source.

Founded in 2015 by a team of industry veterans, the company has built a portfolio of ten transformative drugs ranging from pre-clinical to late stage development in multiple therapeutic areas including oncology, cardiology, dermatology, neurology, and endocrinology. BridgeBio holds each drug candidate in a distinct subsidiary company to maximize management focus and financial flexibility.

BridgeBio’s focus on scientific excellence and rapid execution aims to translate today’s discoveries into tomorrow’s medicines.

Sanuj Ravindran, M.D.

President, CEO & Director

Sanuj K. Ravindran, M.D. is president and CEO of PellePharm. Dr. Ravindran also serves on the PellePharm Board of Directors, and is CEO-in-Residence with BridgeBio, PellePharm’s parent company.

Dr. Ravindran has more than 15 years of strategic and operational biopharma experience. Previously, he was chief business officer at aTyr Pharma (“LIFE”), a clinical stage rare disease-focused biotechnology company, where he led corporate strategy, financial strategy, business development, and investor relations. Prior to that, Dr. Ravindran was senior vice president of corporate development for The Medicines Company (“MDCO”), where he worked to execute multiple transactions totaling more than $2 billion in potential aggregate value. Previously a practicing physician, Dr. Ravindran began his industry career as a venture capitalist for 10 years with Burrill & Company, Radius Ventures, and Asian Healthcare Fund.

Dr. Ravindran is trained in Internal Medicine and completed his residency training at Thomas Jefferson University Hospital. Dr. Ravindran received his B.A. from Northwestern University, his M.D. from Jefferson Medical College and his MBA from the Kellogg School of Management.

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ERVIN EPSTEIN, M.D.

Co-Founder, Director & Chief Medical Officer, PellePharm

Ervin Epstein, M.D. is co-founder, director and chief medical officer of PellePharm. Ervin is a practicing dermatologist and senior scientist at the Children’s Hospital of Oakland Research Institute. Previously, Ervin was a research dermatologist and clinical professor of dermatology at the University of California, San Francisco. Ervin and his colleagues conducted the first randomized trials evaluating chemoprevention of basal cell carcinomas, testing the effects of celecoxib, tazarotene and vismodegib in people with Gorlin syndrome.  His lab also identified dysregulated hedgehog signaling as the molecular defect causing all basal cell carcinomas. Ervin has served as secretary/treasurer and president of the Society for Investigative Dermatology and as a member of the advisory council of the National Institute for Arthritis, Musculoskeletal, and Skin Diseases of the NIH. He is an honorary member of investigative and clinical dermatologic societies worldwide. Ervin earned his M.D. from the University of California, San Francisco and his bachelor’s degree from Harvard University. He is lead author on papers that have appeared in the New England Journal of Medicine, Nature, and Science.

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GERD KOCHENDOERFER, Ph.D.

Vice President, Technical Operations & Program Management, PellePharm

Gerd has more than 20 years of experience in drug development, operations, quality and program management in the biotech and specialty pharma industry. Prior to joining PellePharm, Gerd helped transform Depomed from a small drug delivery company to a specialty pharma company in the pain and neurology space with over $450 million in annual revenue as the executive team member overseeing the technical operations, project management and quality functions. Previously, Gerd held research and drug development management positions at FibroGen, Inc., and Gryphon Therapeutics. During his time, he led more than a dozen drug development programs ranging from early-stage research to NDA approval and multiple global drug development alliances. He was also part of diligence and deal teams responsible for drug licensing and product acquisition transactions cumulatively valued at over $1.5 billion. Gerd earned his Ph.D. in chemistry from the University of California at Berkeley. He has published more than 25 papers in peer-reviewed literature and holds multiple patents.

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ALIX ALDERMAN

Vice President of Regulatory Affairs, PellePharm

Alix Alderman is vice president of regulatory affairs at PellePharm. Prior to joining PellePharm, Alix led all regulatory aspects of global development and strategy for the rare bone disease programs at Ultragenyx as senior director of regulatory affairs. Prior to Ultragenyx, she served as global regulatory lead and director of global product strategy at Abbott/AbbVie. Previously, she held numerous positions of increasing responsibility at Amylin and InterMune, including regulatory affairs leadership for Amylin’s lipodystrophy, obesity and pramlintide early development and commercial franchise. Alix is a member of The Organisation for Professionals in Regulatory Affairs (TOPRA) and has served for many years on the TOPRA Board of Directors. She earned her bachelor’s degree in exercise physiology from the University of California at Davis.

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Sanuj Ravindran, M.D.

President, CEO & Director

Sanuj K. Ravindran, M.D. is president and CEO of PellePharm. Dr. Ravindran also serves on the PellePharm Board of Directors, and is CEO-in-Residence with BridgeBio, PellePharm’s parent company.

Dr. Ravindran has more than 15 years of strategic and operational biopharma experience. Previously, he was chief business officer at aTyr Pharma (“LIFE”), a clinical stage rare disease-focused biotechnology company, where he led corporate strategy, financial strategy, business development, and investor relations. Prior to that, Dr. Ravindran was senior vice president of corporate development for The Medicines Company (“MDCO”), where he worked to execute multiple transactions totaling more than $2 billion in potential aggregate value. Previously a practicing physician, Dr. Ravindran began his industry career as a venture capitalist for 10 years with Burrill & Company, Radius Ventures, and Asian Healthcare Fund.

Dr. Ravindran is trained in Internal Medicine and completed his residency training at Thomas Jefferson University Hospital. Dr. Ravindran received his B.A. from Northwestern University, his M.D. from Jefferson Medical College and his MBA from the Kellogg School of Management.

JEAN TANG, M.D., Ph.D.

Co-Founder, Medical Advisor & Director

Jean Tang, M.D., Ph.D. is co-founder of PellePharm and serves on the PellePharm board of directors. Jean is a practicing dermatologist and associate professor of dermatology at Stanford University. Her research focuses on finding new ways to treat and prevent non-melanoma skin cancer and genetic skin diseases such as Basal Cell Nevus Syndrome and Epidermolysis Bullosa. Jean and her colleagues discovered that hedgehog pathway inhibition could dramatically shrink basal cell carcinoma tumors in patients with Gorlin Syndrome in randomized clinical trials. She has led or co-led four investigator-initiated clinical trials, three of which were focused on basal cell carcinoma treatment or prevention. Jean earned both her M.D. and Ph.D. from Stanford University. She completed her dermatology residency at Stanford and later completed a three-year post-doctorate in mouse genetics at the University of California, San Francisco while simultaneously pursuing formal coursework in biostatistics, epidemiology and clinical trial design.

Ervin Epstein, M.D.

Co-Founder, Director & Chief Medical Officer, PellePharm

Ervin Epstein, M.D. is co-founder, director and chief medical officer of PellePharm. Ervin is a practicing dermatologist and senior scientist at the Children’s Hospital of Oakland Research Institute. Previously, Ervin was a research dermatologist and clinical professor of dermatology at the University of California, San Francisco. Ervin and his colleagues conducted the first randomized trials evaluating chemoprevention of basal cell carcinomas, testing the effects of celecoxib, tazarotene and vismodegib in people with Gorlin syndrome.  His lab also identified dysregulated hedgehog signaling as the molecular defect causing all basal cell carcinomas. Ervin has served as secretary/treasurer and president of the Society for Investigative Dermatology and as a member of the advisory council of the National Institute for Arthritis, Musculoskeletal, and Skin Diseases of the NIH. He is an honorary member of investigative and clinical dermatologic societies worldwide. Ervin earned his M.D. from the University of California, San Francisco and his bachelor’s degree from Harvard University. He is lead author on papers that have appeared in the New England Journal of Medicine, Nature, and Science.

Frank McCormick, Ph.D.

Co-Founder of BridgeBio

Frank McCormick, Ph.D., serves on the PellePharm board of directors. Frank is a professor and director of the University of California, San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center and co-founder of BridgeBio Pharma. Previously, Frank was co-founder and chief scientific officer of Onyx Pharmaceuticals, where he initiated and led drug discovery efforts leading to the approval of ONYX-015 in China for the treatment of nasophryngeal cancer. His group’s research also led to the identification of a CDK4 kinase inhibitor. Prior to Onyx, Frank worked with several Bay Area biotechnology companies, including Cetus Corporation, where he served as director of molecular biology and vice president of research, and Chiron Corporation, where he served as vice president of research. Frank is the David A. Wood Chair of Tumor Biology and Cancer Research at UCSF, and has served as president for the American Association for Cancer Research (AACR). Currently, he oversees an NCI-supported national effort to develop therapies against Ras-driven cancers at the Frederick National Lab for Cancer Research. Frank earned his Ph.D. in biochemistry from the University of Cambridge and his bachelor’s degree in biochemistry from the University of Birmingham in England. He is a Fellow of the Royal Society. He is the author of over 285 scientific publications and holds 20 issued patents.

NEIL KUMAR, Ph.D.

Co-Founder of BridgeBio

Neil Kumar, Ph.D., serves on the PellePharm board of directors. Neil is the chief executive officer of Eidos Therapeutics and chief executive officer and co-founder of its parent company, BridgeBio Pharma. Prior to founding BridgeBio, he was a principal at Third Rock Ventures, where he supported and managed various portfolio companies and focused on new company formation and due diligence. Neil also served as interim vice president of business development and operations for MyoKardiam, Inc., a precision medicine company working on targeted therapies for the treatment of rare cardiovascular diseases. Previously, Neil served as an associate principal at McKinsey & Company, where he developed strategies for pharmaceutical and medical device companies and helped lead personalized medicine efforts. Neil was also involved in the formation of a gene chip company and was a technical consultant for AstraZeneca’s pathway signaling group. Neil earned his Ph.D. in chemical engineering from the Massachusetts Institute of Technology and holds bachelor’s and master’s degrees in chemical engineering from Stanford University. He is the author of several peer-reviewed papers in the fields of oncology and systems biology.

JEAN TANG, M.D., Ph.D.

Co-Founder, Medical Advisor & Director

Jean Tang, M.D., Ph.D. is co-founder of PellePharm and serves on the PellePharm board of directors. Jean is a practicing dermatologist and associate professor of dermatology at Stanford University. Her research focuses on finding new ways to treat and prevent non-melanoma skin cancer and genetic skin diseases such as Basal Cell Nevus Syndrome and Epidermolysis Bullosa. Jean and her colleagues discovered that hedgehog pathway inhibition could dramatically shrink basal cell carcinoma tumors in patients with Gorlin Syndrome in randomized clinical trials. She has led or co-led four investigator-initiated clinical trials, three of which were focused on basal cell carcinoma treatment or prevention. Jean earned both her M.D. and Ph.D. from Stanford University. She completed her dermatology residency at Stanford and later completed a three-year post-doctorate in mouse genetics at the University of California, San Francisco while simultaneously pursuing formal coursework in biostatistics, epidemiology and clinical trial design.

Ervin Epstein, M.D.

Co-Founder, Director & Chief Medical Officer, PellePharm

Ervin Epstein, M.D. is co-founder, director and chief medical officer of PellePharm. Ervin is a practicing dermatologist and senior scientist at the Children’s Hospital of Oakland Research Institute. Previously, Ervin was a research dermatologist and clinical professor of dermatology at the University of California, San Francisco. Ervin and his colleagues conducted the first randomized trials evaluating chemoprevention of basal cell carcinomas, testing the effects of celecoxib, tazarotene and vismodegib in people with Gorlin syndrome.  His lab also identified dysregulated hedgehog signaling as the molecular defect causing all basal cell carcinomas. Ervin has served as secretary/treasurer and president of the Society for Investigative Dermatology and as a member of the advisory council of the National Institute for Arthritis, Musculoskeletal, and Skin Diseases of the NIH. He is an honorary member of investigative and clinical dermatologic societies worldwide. Ervin earned his M.D. from the University of California, San Francisco and his bachelor’s degree from Harvard University. He is lead author on papers that have appeared in the New England Journal of Medicine, Nature, and Science.

Philip Beachy, Ph.D.

Co-Founder